A Comprehensive Manual for Ordinary Level Practical Biology is a book for ordinary level students who are learning the Biology subject, particularly Biology practical activities. Organization of the book has been done systematically and the language used is simple enough to facilitate understanding. This book is divided into six chapters that cover fully the requirements of the Biology syllabus for Ordinary level students. Each chapter is divided into different sections. There is a section for simplified notes that lays the groundwork before doing the practical activities. This is followed by activities (Practical work) in which the required apparatus and items are identified as well as the steps to be followed in conducting experiments. The book is loaded with plenty of diagrams, tables and worked examples, all of which make the learning process easier and memorable to the student. Also, there are exercises that will give the student enough opportunity to practise what has been learned. The author and APE editorial team are confident that this work will be so helpful and resourceful to students on one hand and to teachers and parents or guardians on the other.